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Sexual Health

Peptides researched for their action on melanocortin receptors and vascular response. The core compound is PT-141 (Bremelanotide); also includes oxytocin and kisspeptin.

Peptides: Sexual health

Peptides researched for their action on melanocortin receptors and vascular response. The core compound is PT-141 (Bremelanotide); also includes oxytocin and kisspeptin.

Mechanism and compounds

The representative compound is PT-141 (Bremelanotide), a cyclic 7-amino-acid peptide (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH) from the melanocortin analog family, structurally related to Melanotan II. In this category the interest centers on the melanocortin receptor pathway (MC4R). Oxytocin (a nonapeptide with a disulfide bridge) also appears among compounds related to neuroendocrine response.

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